Vein glue treatment for varicose veins

Without incisions, vein glue treatment seals the affected vein with a medical adhesive

A thin catheter enters the vein through a small needle puncture, and no heat is used. Dr Desmond Ooi offers vein glue treatment as one of four vein closure methods.

Dr Desmond Ooi

Senior Consultant, Advanced Vascular Centre

More than 15 years of experience in vascular and general surgery

Gloved hands holding a vein glue dispenser and its thin catheter beside a bare lower leg on a clinic couch Gloved hands holding a vein glue dispenser and its thin catheter beside a bare lower leg on a clinic couch

Vein glue treatment, laser or radiofrequency, chosen to suit your vein

Glue, laser, radiofrequency and mechanochemical closure all seal the affected vein from inside, and they suit different veins. Glue uses no heat and needs no anaesthetic injected along the vein, while laser and radiofrequency have more long-term evidence. Which one suits your leg depends on the shape of your vein and the pattern of leaking on your duplex scan.

How vein glue treatment seals the affected vein from the inside

Vein glue treatment is a minimally invasive treatment for varicose veins. It involves using a medical adhesive that is injected into the affected vein, sealing it shut and redirecting blood flow to healthier veins. This procedure eliminates the need for incisions, making it a comfortable option for patients seeking relief from varicose veins.

The method is also called cyanoacrylate closure, after the type of medical adhesive it uses, or glue therapy for varicose veins.

Diagram of a thin catheter sealing a leg vein with medical adhesive
A thin catheter sealing a leg vein with medical adhesive, in a drawing not to scale

The procedure is a relatively quick one with a few steps.

  1. A thin catheter entering a leg vein through a needle puncture, with an ultrasound probe on the skin

    A catheter is inserted into the affected vein, with a small amount of local anaesthetic where it goes in.

  2. A small amount of medical adhesive leaving the tip of a catheter inside a leg vein

    The adhesive is delivered into the catheter.

  3. Light pressure on the skin over the vein while its walls stick together

    Light pressure is applied so the vein walls can stick together and close off.

  4. The sealed vein after the catheter is removed, with blood flowing through a healthy vein

    The catheter is removed.

This treatment process is guided by imaging techniques such as ultrasound to ensure accuracy and precision.

Who glue closure suits, based on the duplex ultrasound scan

Glue closure is used to address the symptoms and complications associated with varicose veins. Varicose veins occur when the valves in the veins malfunction, causing blood to pool and the veins to become enlarged and twisted. This can result in discomfort, pain, swelling, and cosmetic concerns.

Glue closure offers a solution by sealing off the diseased veins, redirecting blood flow to healthier veins and improving circulation. It helps alleviate symptoms such as pain, heaviness, and leg fatigue, enhancing the overall quality of life for individuals with varicose veins.

Dr Desmond Ooi offers vein glue treatment in Singapore as a minimally invasive alternative to patients suffering from varicose veins or venous ulcers.

Before glue closure, patients will typically undergo a pre-procedure evaluation, including ultrasound testing. This diagnostic procedure helps Dr Desmond Ooi accurately assess the affected veins and determine the most appropriate treatment plan. The ultrasound allows for a detailed visualisation of the veins, their size, and any underlying issues, enabling precise targeting during the procedure.

Glue closure may be considered when a method without heat is preferred, when avoiding a series of anaesthetic injections along the vein matters to you, and when the shape of the vein suits it. Patients who are allergic to the adhesive or have vein inflammation are not good candidates for the treatment. If glue does not suit your vein, another closure method, or open surgery, may be chosen instead.

Bulging varicose veins on the back of one calf Varicose veins and their symptoms

The day of the procedure, from arriving to walking home

Vein glue treatment is a day procedure, carried out under ultrasound guidance. How long it takes depends on the number of veins treated and how complex they are.

  1. After the procedure, you will be taken into a recovery room to rest and recover from the treatment
  2. You are usually asked to walk for 20 to 30 minutes before you leave
  3. You go home the same day

Varicose vein glue treatment recovery, from walking to returning to work

After undergoing glue closure, the recovery period is relatively short. Patients can expect to resume their daily activities quickly. As a guide:

  • Normal daily activities:

    within 24 hours

  • Back to work:

    Dr Ooi gives a two-week medical certificate, and some patients may return within 4 to 5 days

  • Driving:

    once you can safely make an emergency stop

  • Strenuous exercise:

    after 1 to 2 weeks

It is important to take it easy during the initial recovery phase and avoid engaging in vigorous exercise or activities that may strain the treated area. However, gentle walking is encouraged as it promotes blood circulation and aids in the healing process.

An older person walking along a clinic corridor

Mild bruising may occur around the treated area, but this is a common and temporary side effect that will fade over time. Compression stockings are often not needed after glue closure. Many patients are reviewed several weeks later, and a follow-up scan may be arranged to check that the vein has closed.

It is advised to follow the specific post-procedure instructions provided by our medical team to ensure optimal recovery.

Risks and side effects of glue closure, from bruising to allergy

While glue closure is a safe and effective treatment for varicose veins, there are potential risks and complications associated with the procedure. These may include:

  • Deep vein thrombosis
  • Infection and inflammation of the vein
  • In rare cases, an allergic reaction to the adhesive

Other vein glue side effects include mild bruising or tenderness, temporary inflammation along the treated vein, darker skin over it, and the vein not closing fully or reopening later.

Consult Dr Desmond Ooi and discuss any concerns or specific medical conditions before undergoing glue closure.

Glue closure compared with laser, radiofrequency and surgery

Glue, laser, radiofrequency and mechanochemical closure all aim to close the faulty vein so that blood is redirected into healthy veins. They differ in how the vein is closed, the anaesthetic needed, the recovery, and how much long-term evidence there is.

Laser and radiofrequency treatment close the vein with heat, so local anaesthetic is injected along the vein to protect the tissue around it. Glue closure and mechanochemical ablation use no heat, so they need no anaesthetic injected along the vein.

A 2025 review found fewer nerve injuries and burns with the methods that use no heat, which may matter most below the knee, but a slightly lower rate of the vein staying closed, and their long-term evidence is more limited.

Stripping and ligation is open surgery, kept for selected veins whose shape makes a catheter treatment less suitable, or for veins that come back after earlier treatment. Sclerotherapy injections treat smaller veins.

Portrait in a navy suit and red tie, arms crossed

Dr Desmond Ooi is a General Surgeon whose clinical interest is vascular surgery

  • BM (Southampton), MMed Surgery (NUS), FRCS (Edinburgh)

He received specialised vascular and endovascular training in the UK, and was formerly Patient Safety Officer at Khoo Teck Puat Hospital.

More about Dr Ooi

Varicose vein glue treatment cost, MediSave and insurance

First visit, consultation and scan:
quoted when you write in
Surgeon's fee, laser treatment of one leg:
from SGD 5,341 (opens the Ministry of Health page)
For medically indicated procedures MediSave claimable Insurance claimable

What will you pay in cash?

Paying with MediSave and insurance

For varicose vein day surgery that is medically indicated, MediSave may help, and an Integrated Shield Plan may also cover it, subject to your plan and panel.

Personal

Prudential
Great Eastern
Income
Inova Care
Singlife
AIA

Corporate

Alliance Medinet
MHC
DA
Parkway Shenton
iXchange
Fullerton Health
AIA
HSBC Life
Cigna
Great Eastern
Income
Prudential
Singlife
Tokio Marine
BetterHealth
QBE
soda by DA
NOW Health International
Aon Care
Allianz Care

Vascular clinics at Mount Elizabeth and Mount Alvernia

Mount Elizabeth Hospital entrance

Advanced Vascular Centre, Mount Elizabeth

#13-06 Mount Elizabeth Medical Centre

+65 6737 1180

Mount Alvernia Hospital entrance

Advanced Vascular Centre, Mount Alvernia

Medical Centre D, #07-58, 820 Thomson Road

+65 6265 8820

Questions patients ask about vein glue treatment

How painful is vein glue treatment?

Vein glue treatment causes minimal pain similar to a needle prick.

Patients may experience some bruising or soreness after the procedure that will subside after a couple of days.

What are the disadvantages of glue closure?

It has less long-term outcome data than laser and radiofrequency treatment, and a 2025 review found a slightly lower rate of the vein staying closed with the methods that use no heat.

Its adhesive delivery system generally makes it one of the more expensive vein treatments.

Patients who are allergic to the adhesive are not good candidates, and an allergic or inflammatory reaction to it is uncommon.

How long does glue closure last?

A treated vein occasionally reopens over time, but new varicose veins more often come from another vein whose valves fail later.

Glue closure also has less long-term outcome data than laser and radiofrequency treatment.

A careful duplex scan before treatment, and treating every leaking vein that matters, lowers the chance of veins coming back.

Which is better for my veins, glue or laser treatment?

No single treatment suits everyone.

Laser and radiofrequency treatment have more long-term evidence, while glue uses no heat and needs no anaesthetic injected along the vein.

Which suits you depends on the shape of your veins and the pattern of leaking on your scan.

How much does vein glue treatment cost?

For the surgeon's fee, this page shows the nearest listed procedure, laser treatment of one leg, from SGD 5,341 with GST.

The adhesive delivery system generally makes glue one of the more expensive vein treatments.

Hospital, anaesthetist and device charges are billed separately and given to you as a written estimate before surgery.

What is the success rate of glue closure?

Published figures vary with the vein treated and how each study measured success, so this page does not quote one.

A 2025 review found a slightly lower rate of the vein staying closed with the methods that use no heat than with laser or radiofrequency treatment.

Is glue closure safe?

Like any procedure, it carries some risks, which are listed on this page.

Patients who are allergic to the adhesive or have vein inflammation are not good candidates for the treatment.

Can glue closure cause blood clots?

Wrongly injecting a deep vein can cause blood clots. Therefore, glue closure should only be done by a licensed professional.

A clot in a deep vein after treatment is rare.

What happens to the vein after glue closure?

Once the vein wall is closed off, the body will absorb the affected vein.

Will my blood flow normally after glue closure?

Blood flow will return to normal after glue closure. The body will absorb the treated veins, and blood will flow through healthy veins.

In fact, glue closure can improve blood flow by reducing the amount of blood that pools in the affected veins.

Do I need to stay in hospital?

Vein glue treatment is a day procedure, and patients usually walk immediately and go home the same day.

Is vein glue treatment covered by MediSave or insurance?

For varicose vein day surgery that is medically indicated, MediSave may help, and an Integrated Shield Plan may also cover it, subject to your plan and panel.

Start with a question

If you are unsure whether vein glue treatment suits your veins, message the clinic. You can ask before you arrange anything. Family members can also message on a patient's behalf.

Dr Desmond OoiRequest an appointment